Condition Lookup
Sub-Category:
Chronic Inflammatory Disorders
Number of Conditions: 2
Chronic Urticaria
Specialty: Allergies and Immunology
Category: Other Related Disorders
Sub-category: Chronic Inflammatory Disorders
Symptoms:
itchy hives lasting longer than six weeks; angioedema (swelling beneath the skin); recurrent flare-ups without clear triggers
Root Cause:
Persistent activation of mast cells and histamine release in the skin without an identifiable allergen.
How it's Diagnosed: videos
Diagnosed clinically by recurrent hives lasting >6 weeks without identifiable triggers.
Treatment:
Treated with antihistamines, leukotriene receptor antagonists, and immunomodulators (e.g., omalizumab).
Medications:
H1 antihistamines (e.g., Cetirizine , Loratadine ), H2 blockers (e.g., Ranitidine), and biologics (e.g., Omalizumab ).
Prevalence:
How common the health condition is within a specific population.
Approximately 1% of the population; more common in women and young adults.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Autoimmune disorders; Chronic stress; Thyroid disease; Infections
Prognosis:
The expected outcome or course of the condition over time.
Most cases resolve within 1–5 years; some may persist for decades.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Impaired quality of life; Sleep disturbances; Emotional distress; Anaphylaxis (rare in chronic idiopathic cases)
Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)
Specialty: Allergies and Immunology
Category: Other Related Disorders
Sub-category: Chronic Inflammatory Disorders
Symptoms:
nasal congestion; loss of smell; runny nose; facial pain or pressure; recurrent sinus infections
Root Cause:
Persistent inflammation of the nasal and sinus mucosa, often involving Type 2 inflammation (elevated eosinophils and IgE).
How it's Diagnosed: videos
.Diagnosed via clinical exam, nasal endoscopy, and CT imaging.
Treatment:
Treated with intranasal corticosteroids, biologics (e.g., dupilumab), and sometimes surgical removal of polyps.
Medications:
Intranasal corticosteroids (e.g., Fluticasone ), leukotriene receptor antagonists (e.g., Montelukast ), and biologics (e.g., Dupilumab ).
Prevalence:
How common the health condition is within a specific population.
Affects up to 4% of the general population; higher in adults over 40 years.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Asthma; Aspirin sensitivity; Allergies; Cystic fibrosis; Smoking
Prognosis:
The expected outcome or course of the condition over time.
Good with appropriate management, but polyps may recur even after surgery.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Chronic sinus infections; Asthma exacerbations; Obstructive sleep apnea