Background

Condition Lookup

Sub-Category:

Eosinophilic Disorders

Number of Conditions: 2

Eosinophilic Esophagitis (EoE)

Specialty: Allergies and Immunology

Category: Other Related Disorders

Sub-category: Eosinophilic Disorders

Symptoms:
difficulty swallowing; food impaction; chest pain; heartburn; abdominal pain; vomiting in children; failure to thrive in children

Root Cause:
Chronic immune-mediated inflammation of the esophagus with eosinophil infiltration, often triggered by food allergens.

How it's Diagnosed: videos
Upper endoscopy with esophageal biopsy showing eosinophilic infiltration; allergy testing may identify triggers.

Treatment:
Elimination diets, proton pump inhibitors, corticosteroids (topical or systemic), and esophageal dilation for strictures.

Medications:
Proton pump inhibitors (e.g., Omeprazole ), topical corticosteroids (e.g., Fluticasone ), and elimination diets.

Prevalence: How common the health condition is within a specific population.
Approximately 1 in 2,000 individuals in the U.S.; more common in males.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
Personal or family history of allergic diseases, including asthma, eczema, or food allergies.

Prognosis: The expected outcome or course of the condition over time.
Good with proper treatment, but symptoms often recur if treatment is stopped.

Complications: Additional problems or conditions that may arise as a result of the original condition.
Esophageal strictures, food impaction, and chronic inflammation leading to fibrosis.

Eosinophilic Gastroenteritis

Specialty: Allergies and Immunology

Category: Other Related Disorders

Sub-category: Eosinophilic Disorders

Symptoms:
abdominal pain; nausea; diarrhea; vomiting; weight loss; fatigue; anemia

Root Cause:
Eosinophilic infiltration of the gastrointestinal tract, likely triggered by food or environmental allergens.

How it's Diagnosed: videos
Endoscopy with biopsy showing eosinophilic infiltration, imaging studies, and blood tests for eosinophilia.

Treatment:
Elimination diets, corticosteroids, and symptom management (e.g., anti-nausea medications).

Medications:
Corticosteroids (e.g., Prednisone ) and dietary modifications.

Prevalence: How common the health condition is within a specific population.
Rare; precise prevalence is unknown.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
Allergic diseases, family history of eosinophilic disorders, and certain infections.

Prognosis: The expected outcome or course of the condition over time.
Chronic but manageable with treatment; symptoms may relapse without ongoing management.

Complications: Additional problems or conditions that may arise as a result of the original condition.
Bowel obstruction, malabsorption, and perforation in severe cases.