Condition Lookup
Sub-Category:
Ichthyosis (Dry, Scaly Skin)
Number of Conditions: 2
Ichthyosis Vulgaris
Specialty: Dermatology
Category: Genetic Skin Disorders
Sub-category: Ichthyosis (Dry, Scaly Skin)
Symptoms:
dry, scaly skin; fine, white or gray scales on arms, legs, or trunk; thickened palms and soles; worsens in cold, dry weather
Root Cause:
Mutation in the FLG gene affecting filaggrin production, leading to impaired skin barrier and moisture retention.
How it's Diagnosed: videos
Clinical examination; family history and genetic testing for confirmation.
Treatment:
Emollients, keratolytics, and topical retinoids to improve hydration and reduce scaling.
Medications:
Urea-based or lactic acid-based moisturizers – to soften scales. Topical retinoids – for severe cases.
Prevalence:
How common the health condition is within a specific population.
Affects about 1 in 250 individuals.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Family history, atopic dermatitis.
Prognosis:
The expected outcome or course of the condition over time.
Lifelong condition; manageable with regular treatment.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Skin infections due to barrier dysfunction; Psychological distress
Lamellar Ichthyosis
Specialty: Dermatology
Category: Genetic Skin Disorders
Sub-category: Ichthyosis (Dry, Scaly Skin)
Symptoms:
large, dark, plate-like scales; tightness of skin; ectropion (eyelid eversion); palmar and plantar thickening
Root Cause:
Mutations in genes like TGM1, leading to defective lipid metabolism and impaired skin barrier.
How it's Diagnosed: videos
Clinical examination; genetic testing for confirmation.
Treatment:
Emollients, keratolytics, and systemic retinoids for severe cases.
Medications:
Urea-based or lactic acid-based moisturizers – to reduce scaling. Oral retinoids (e.g., acitretin ) – for severe cases.
Prevalence:
How common the health condition is within a specific population.
Rare, about 1 in 100,000 individuals.
Risk Factors:
Factors or behaviors that increase the likelihood of developing the condition.
Autosomal recessive inheritance.
Prognosis:
The expected outcome or course of the condition over time.
Chronic but manageable with consistent treatment.
Complications:
Additional problems or conditions that may arise as a result of the original condition.
Infections; Ectropion; Overheating due to impaired sweating