Background

Condition Lookup

Sub-Category:

Nail Tumors

Number of Conditions: 2

Subungual Melanoma

Specialty: Dermatology

Category: Nail Disorders

Sub-category: Nail Tumors

Symptoms:
dark streak or discoloration under the nail; irregular pigmentation; nail destruction; bleeding or ulceration

Root Cause:
Malignant proliferation of melanocytes in the nail matrix.

How it's Diagnosed: videos
Clinical examination; dermoscopy and biopsy for confirmation.

Treatment:
Surgical excision with wide margins; systemic therapies for advanced disease.

Medications:
Immunotherapy (e.g., pembrolizumab ) – for metastatic cases. Targeted therapy (e.g., BRAF inhibitors) – for certain mutations.

Prevalence: How common the health condition is within a specific population.
Rare, more common in older adults.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
UV exposure, trauma, family history of melanoma.

Prognosis: The expected outcome or course of the condition over time.
Poor if detected late; early detection improves survival.

Complications: Additional problems or conditions that may arise as a result of the original condition.
Metastasis; Nail loss

Glomus Tumors

Specialty: Dermatology

Category: Nail Disorders

Sub-category: Nail Tumors

Symptoms:
painful, bluish-red nodule under the nail; exquisite tenderness to cold; nail deformity

Root Cause:
Benign tumor of glomus bodies, which regulate thermoregulation in the skin.

How it's Diagnosed: videos
Clinical examination, imaging (MRI), or biopsy.

Treatment:
Surgical excision.

Medications:
Not applicable; treatment is surgical.

Prevalence: How common the health condition is within a specific population.
Rare, often misdiagnosed.

Risk Factors: Factors or behaviors that increase the likelihood of developing the condition.
None known; sporadic occurrence.

Prognosis: The expected outcome or course of the condition over time.
Excellent with surgical removal.

Complications: Additional problems or conditions that may arise as a result of the original condition.
Recurrence; Persistent pain